Maybe you can already do this with ClrMamePro, and I just don't know about it:

It'd be great if you could prepare a list of the games you didn't care about, so that ClrMame could remove them when it showed lists of your missing games. That way, you could really see which games you were "missing" (that is, games you might actually want), rather than having to weed through a list of ALL missing games each time.

Cheers, Zeppy