I noticed that in some cases the buttons are not drawn anymore. The sequence that reproduces the problem for me (at least most of the time) is the following: Change the buttons to a custom bitmap (e.g. drdoom), close clrmame pro, start it again, and close the profiler window and the buttons are gone (areas are grey). It never happens with the standard buttons. You can change the buttons back to the custom buttons and they will be drawn perfectly ok as long as you do not exit clrmame pro again. I have been using the drdoom buttons almost from the start and never saw any problems so far. I am using version 3.89a on Windows XP.