Using Windows Vista here myself (and also 7zip). No issues. The priority options are only used for some internal threads which are not used at all or very limited when the profiler reads in the profiles....
Well...>100 profiles need some time to read in, but this usually takes maybe 8 seconds for 1000 or something. As mentioned, if your *.cmp files were created with an external tool, it might be slow. If you like you can rar/7z/zip up your complete clrmame folder and send it to me for testing somehow.


Roman Scherzer