GameEx is a graphical DirectX based front-end for MAME, Zinc, Daphne, PC Games, and all command line based game emulators, along with being a complete Home Theatre PC solution.

Here's whatsnew:
Setup wizard now features a search for setting feature.
Includes Ben Bakers LCD/LED Plugin
Plugin system 1.3 with included .net 2.0 source code templates
Speech plugin now speaks game descriptions
New plugn - random arcade sound
For registered users theres a PDF game manual viewer for MAME and emulators
New setting to disable the game information page at the emulator level
New setting to have gameex not hide the windows taskbar
Picture and slideshows now show the GameEx toolbar when the mouse is active
The progress dialog bar when playing videos and dvds now takes up less screen space
GameEx should startup and run faster
Fixes menu crash issue with certain themes
Fixes games not launching when game information page is disabled in certain configurations
Fixes display issues with certain fonts
There's more but that's the main changes

Get it here:
http://tomspeirs.com/GameEx/default.aspx

-Trebor