Here's whatsnew:
[Xe] Fixed unaligned RGB flipped rendering
[Xe] Soft zoom 1x1 when speed control is disabled
[Xe] Modified NVRAM handling
[Xe] Modified RAM Cart and Memory Card naming
[Xe] YUV Rendering support
[Xe] Improved fullscreen switching
[Xe] Sub Channel support for CD-ROM and CD Images
[Xe] Playback support
[Xe] Support for up to 6 Players
[Xe] Various UI tweaks
[Xe/Linux] Xe For PPC64
[Xe/Linux] Fixed improper ALSA syncing
[Xe/Win32 UI is now built with GTK+
[PC Engine] Fixed VDC DMA timings
[Famicom] Added Multi-Tap Support
[Famicom/FDS] Fixed disk type detect
[Mark III] Fixed SRAM size
[PC Engine] Added 3 Button pad
[PC Engine] Modified Multi-Tap Support
[Mega Drive] Added Multi-Tap Support
[Super Famicom] Fixed serial controller read
[Super Famicom] Added Multi-Tap Support
[Neo Geo] Support various protection devices
[Neo Geo CD] Fixed IRQ Controller levels
[Wonder Swan] Fixed MUL instruction
[Wonder Swan] Added (and now requires) BIOS support
[Game Boy] Fixed Memory Leak
[Game Boy] Fixed MBC2 BRAM size (Thanks to Cuban D. for finding this bug)
Many other changes / improvements, too numerous to list

Get it here:
http://www.xe-emulator.com/index.php?m=download

-Trebor